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KMID : 1103920110170030229
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Korean Journal of Hepatology
2011 Volume.17 No. 3 p.229 ~ p.232
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A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
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Kim Ju-Seung
Jang Young-Rock
Lee Ji-Won
Kim Jin-Yong
Jung Young-Kul
Chung Dong-Hae
Kwon Oh-Sang
Kim Yun-Soo
Choi Duck-Joo
Kim Ju-Hyun
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Abstract
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Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present a case of a 39-year-old woman who was diagnosed with abdominal actinomycosis and received amoxicillin treatment. The patient displayed hepatocellular and bile-duct injury, in addition to elevated levels of liver enzymes. The patient was diagnosed with amoxicillin-induced cholestatic hepatitis. When amoxicillin was discontinued, the patient’s symptoms improved and her liver enzyme levels reduced to near to the normal range.
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KEYWORD
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Drug-induced liver injury, Amoxicillin, Cholestatic hepatitis
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